Heat stress (HS) results from exposure to a temperature condition beyond the optimum range of an organism. Following heat stress, cells exhibit a heat-shock response (HSR), which is a highly-conserved and prominent pathway with a series of stress-inducible gene expression, to increase thermal tolerance and facilitate cellular recovery. C. elegans Heat-Shock Model https://c-elegans.creative-biogene.com/c-elegans-heat-shock-model-service.html